Senior/Junior Haematology Clinical Trials Research Fellow

NHS
Manchester, England
5 months ago
Applications closed

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Posted
20 Nov 2025 (5 months ago)
Job Summary

The Haematology and TYA services are seeking to appoint a senior/junior Haematology Clinical Trials Research Fellow to work alongside the research team and existing roles within the Palatine treatment centre. The service is part of The Christie, a leading cancer centre with a history of world firsts and over 100 years of advancement in cancer treatment and care. The Palatine treatment centre opened in 2014 as a purpose‑built facility for the Haematology and Transplant Unit and Teenage and Young Adult (TYA) services. The stem cell transplant programme at the Christie was established in 1982 and now performs 120‑160 transplants a year. The unit is fully accredited for JACIE and has delivered CAR‑T therapy.


Main Duties of the Job

The role offers an exciting opportunity to increase clinical research experience including the delivery of innovative early phase research in compliance with Good Clinical Practice and Trust policy. The post holder, with consultant oversight and alongside the research team, will be responsible for seeing new referrals, follow‑ups and for managing the patient throughout all aspects of their trial experience. In addition, this post will allow the successful candidate unique opportunities to gain experience in clinical management of intensively treated Haematology Oncology patients including management of patients receiving novel cellular therapies (CAR‑T cell therapy) and stem cell transplantation. This is a 10‑session non‑training speciality registrar level role. The position is suitable for individuals in the second half or upon completion of their specialist training who wish to gain further experience in clinical research, including first‑in‑human trials. LTFT applicants are eligible to apply as job share will be considered. Salary will be on the NHS scale in line with appropriate clinical experience.


About Us

The Christie is one of Europe’s leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% of patients are referred to us from other parts of the country. We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years. We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.


Details

  • Date posted: 04 November 2025
  • Pay scheme: Hospital medical and dental staff
  • Grade: Doctor - other
  • Salary: £52,656 to £73,992 a year pro rata
  • Contract: Fixed term
  • Duration: 6 months
  • Working pattern: Full‑time
  • Reference number: 413‑MD‑C2025‑24662‑OO
  • Job locations: Car T - E00754, Manchester, M20 4BX

Clinical Trials

The position is suitable for individuals who wish to gain further experience in experimental medicine & Phase I trials, including first‑in‑human trials. A diverse range of clinical research trials are in progress & following training, the post holder will participate in these studies as a co‑/sub‑investigator. These include Phase I trials of small molecule inhibitors, combination / multi‑modality Phase I trials, and trials of CAR‑T and bispecific antibodies. The post holder will be involved in managing all aspects of trial patients (both in outpatient & in‑patients setting), across all areas of haematological malignancy, through new patient consultation, consent & screening patients & reviewing patients at follow‑up appointments.


The post holder will attend Safety Review Committee meetings (usually remotely) to discuss trial patients. This will involve close liaison with Principal Investigators, referring consultant body across the north of England and Wales & other team members. The appointee will interface with external stakeholders such as CROs & pharmaceutical sponsors.


The appointee will undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to be involved in the development & planning of new studies.


The Fellow will maintain a level of continuing professional development. There is the potential to present research work & the post holder will be expected to be involved in writing papers & reviews. The post holder will also be required to undergo an annual appraisal.


The Fellow will be expected to contribute to both undergraduate & postgraduate teaching, and aspects of clinical governance & audit.


Inpatient and Day Unit

The Haematology Fellow will join the existing Palatine ward Haematology clinical team, ensuring that all patients across the department have optimal daily clinical cover. Working as part of the existing ward team (2 Haematology ST doctors, 1 TYA Oncology Senior clinical fellow, 1 Junior Oncology fellow and 3 ward‑based IMTs covering a 31‑bed ward), the haematology fellow will have a particular responsibility for supervision of patients on the new 4 inpatient bedded unit opened early 2021 and the adjacent ambulatory care unit. The Haematology service is supported by an attending consultant, with 2 scheduled consultant ward rounds per week and daily consultant level input as required.


Outpatients

There will be an opportunity to attend the Haematology departmental weekly teaching sessions and to participate in Haematology outpatient clinics focusing on patients enrolled in clinical trials.


Person Requirements

Flexible working and cross‑cover with existing Palatine Ward middle grade haematology roles (Haematology Specialist Registrars and the Trust Grade post) will be a requirement within this post. The post holder will require good communication skills to work effectively and collaboratively within the broader teams, to engage and build rapport with patients and their families undergoing complex oncology/Haematology treatments. The post holder will be flexible, adaptable and communicate positively at all times, providing information at an appropriate level of understanding and communicating with patients, families and carers with empathy and reassurance. Good time‑management/organisational skills to prioritise the patient workload are essential.


Research, Audit and Quality Improvement

The post holder will develop knowledge of research governance, clinical governance, research ethics and work within and comply with Good Clinical Practice (ICH GCP). They will support clinical audits, report results, implement change where necessary, disseminate relevant research findings to colleagues and members of the health professions via presentation and publication, and contribute to the Trust’s governance processes and framework.


Continuing Professional Development

The Trust supports the requirements for continuing professional development (CPD) as laid down by the GMC and surgical colleges and is committed to providing time and financial support for these activities.


Person Specification

Qualifications (Essential)



  • MRCP or equivalent
  • Primary medical qualification (MBBS or equivalent)
  • GMC registration

Qualifications (Desirable)



  • FRCPath or equivalent
  • Good Clinical Practice
  • Higher degree

Training (Essential)



  • Experience in managing acutely unwell patients undergoing chemotherapy

Training (Desirable)



  • ALS certificate in date
  • Evidence of clinical leadership skills

Experience (Essential)



  • Experience managing Haematology inpatients
  • Interest and documented experience in Clinical Audit

Experience (Desirable)



  • Conference presentations

Teaching (Essential)



  • Documented experience of ward based peer‑to‑peer teaching or teaching of undergraduates

Teaching (Desirable)



  • Teaching qualification

Personal Skills (Essential)



  • Excellent written and oral communication skills
  • Flexibility, commitment and compatibility with colleagues and multidisciplinary staff in the department
  • Reliable work record

Motivation (Essential)



  • Committed to career pathway in Haematology
  • Aspiration to develop extensive clinical experience in Haematology Oncology including novel high intensity therapies

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.


UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website.


Employer Details

The Christie NHS FT
Car T - E00754
Manchester
M20 4BX


Employer Website

https://www.christie.nhs.uk/


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