Senior/Junior Haematology Clinical Trials Research Fellow | The Christie NHS Foundation Trust

The Haematology and TYA services are seeking to appoint a senior/junior Haematology Clinical Trials Research Fellow to work alongside the research team and existing roles within the Palatine treatment centre. In 2014 the Palatine treatment centre opened as a purpose‑built facility for the Haematology and Transplant Unit and Teenage and Young Adult (TYA) services. Many clinical and scientific staff members have contributed to research, education and clinical developments, making The Christie proud to be responsible for having ‘world firsts’ and playing a crucial role in the advancement of cancer treatments and care for over 100 years.

The stem cell transplant programme at The Christie was established in 1982 and has undertaken almost 3000 procedures. The department currently performs 120–160 transplants per year. In 2018 the Christie was selected as one of seven first‑wave UK centres for delivery of CAR‑T therapy. The unit is fully accredited for treatment with JACIE and the first patients were treated in 2019.

The role offers an exciting opportunity to increase clinical research experience, including the delivery of innovative early‑phase research in compliance with Good Clinical Practice & Trust policy. The post holder, with consultant oversight and alongside the research team, will be responsible for seeing new referrals, follow‑ups and for managing the patient throughout all aspects of their trial experience. The position allows unique opportunities to gain experience in clinical management of intensively treated haematology oncology patients, including the management of patients receiving novel cellular therapies (CAR‑T cell therapy) and stem cell transplantation.

This is a 10‑session non‑training speciality registrar level role. The position is suitable for individuals in the second half / upon completion of their specialist training who wish to gain further experience in clinical research, including first‑in‑human trials. LTFT applicants are eligible to apply as job share will be considered.

Salary will be on the NHS scale in line with appropriate clinical experience. Interested candidates are encouraged to discuss this ahead of any application. Depending on interest and experience, the post holder will be able to participate in the SpR on‑call rota, which will attract a banding supplement.

The Christie is one of Europe’s leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% of patients are referred to us from other parts of the country. We provide radiotherapy, chemotherapy, highly specialist surgery and a wide range of support and diagnostic services. We also run one of the largest early clinical trial units in Europe with over 300 trials every year, making us an international leader in research.

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• The position is suitable for individuals who wish to gain further experience in experimental medicine & Phase I trials, including first‑in‑human trials.
  
• A diverse range of clinical research trials are in progress. After training, the post holder will participate in these studies as a co‑/sub‑investigator, including Phase I trials of small molecule inhibitors, combination/multi‑modality Phase I trials, and trials of CAR‑T and bispecific antibodies.
  
• The post holder will be involved in managing all aspects of trial patients (both in outpatient and in‑patient settings) across all areas of haematological malignancy, through new patient consultation, consent & screening of patients, and reviewing patients at follow‑up appointments.
  
• The post holder will attend Safety Review Committee meetings (usually remotely) to discuss trial patients, involving close liaison with Principal Investigators, referring consultant bodies across the north of England and Wales & other team members.
  
• The post holder will interface with external stakeholders such as CROs & pharmaceutical sponsors.
  
• The post holder will undertake the administrative duties associated with the care of their patients, be encouraged to be involved in the development & planning of new studies, maintain a level of continuing professional development, and present research work, write papers & reviews, and undergo an annual appraisal.
  
• The post holder will contribute to undergraduate & postgraduate teaching, and aspects of clinical governance & audit.
  

The Haematology Fellow will join the existing Palatine ward Haematology clinical team ensuring that all patients across the department have optimal daily clinical cover. Working as part of the existing ward team which includes 2 Haematology ST doctors, 1 TYA Oncology Senior clinical fellow, 1 Junior Oncology fellow and 3 ward‑based IMTs covering the 31‑beded ward, the haematology fellow will have particular responsibility for supervision of patients on the new 4‑inpatient bedded unit due to open early 2021 and the adjacent ambulatory care unit.

The Haematology service is supported by an attending consultant, with 2 scheduled consultant ward rounds per week and daily consultant level input as required.

There will be an opportunity to attend the Haematology departmental weekly teaching sessions and to participate in Haematology outpatient clinics focusing on patients enrolled in clinical trials.

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• Flexible working and cross‑cover with existing Palatine Ward middle‑grade haematology roles (Haematology Specialist Registrars and the Trust Grade post) will be a requirement within this post.
  
• Good communication skills to work effectively and collaboratively within the broader teams, engage and build rapport with patients and their families undergoing complex oncology/haematology treatments, communicate positively at all times, provide information at an appropriate level of understanding, and manage the patient workload with good time‑management/organisation.
  

The post holder will develop knowledge of research governance, clinical governance, research ethics and work within and comply with the principles of Good Clinical Practice (ICH GCP). They will support clinical audits, report results, implement change, disseminate findings via presentation and publication, and work within and contribute to the Trust’s governance processes and framework.

The Trust supports the requirements for continuing professional development (CPD) as laid down by the GMC and surgical colleges and is committed to providing time and financial support for these activities.

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• Period
  
• Monday
  
• Tuesday
  
• Wednesday
  
• Thursday
  
• Friday
  
• AM
  
• CRF Early Phase Clinic
  
• CRF ward round
  
• CRF Early Phase and Haem Research Clinic
  
• CRF ward round
  
• Palatine Ward
  
• 8am Education Meeting
  
• CRF ward round
  
• Research Administration (SAE query resolution, trial safety meetings)
  
• Haematology Day Unit
  
• PM
  
• New patient trials clinic (HTDU)
  
• 13:00-14:00- CTC Meeting
  
• 14.00 onwards
  
• Ambulatory care
  
• Clinic admin
  
• 15:00 - MDT
  
• 13:00 Trial patient planning and prioritization meeting
  
• Ambulatory Care
  
• Research/ audit project work.
  
• 16:00 Handover (if on call)
  

This advert closes on Tuesday 18 Nov 2025.