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Senior Scientist

Oxford
6 days ago
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Company Overview:
I am working with an innovative biotechnology company developing a cutting-edge LNP platform to advance mRNA vaccines and therapeutics across a wide range of diseases. Their mission is to make mRNA-based treatments accessible to everyone, everywhere, addressing critical global health challenges such as antibiotic resistance, cancer, and viral illnesses. They aim to be a leader in the life sciences sector by applying advanced science and technology to improve human health.

Role Overview:
We are seeking a highly motivated Senior Scientist – Formulation to join our R&D team. The successful candidate will play a key role in the design, development, and optimization of nanoparticle-based formulations for mRNA pharmaceuticals. This position requires strong expertise in nanoparticles, biomaterials, and polymers, with hands-on experience in formulation development and characterization.

Key Responsibilities:



Lead the development of nanoparticle formulations for mRNA therapeutics.

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Design experimental study plans to optimize formulations for specific RNA constructs and therapeutic applications.

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Develop nanoparticle manufacturing processes for in-house use and transfer to external GMP facilities.

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Collaborate closely with cross-functional teams, including RNA synthesis, biology, and analytics.

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Prepare technical documents, reports, and presentations for management and external partners.

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Maintain high standards of quality, reproducibility, and rigor in experimental research and development activities.

Education & Experience:

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Ph.D. in Chemistry, Pharmaceutical Sciences, Biology, Physics, or a related field with a focus on bio- or nano-materials.

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Demonstrated expertise and practical experience in nanoparticle assembly and characterization, preferably lipid- or polymer-based nanoparticles.

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Strong knowledge of biophysical and physicochemical characterization techniques (e.g., SAXS, DSC, NMR, LC-MS, HPLC, DLS, TEM).

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1–2 years of relevant industry experience is advantageous.

Required Skills & Abilities:

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Highly organized, self-motivated, and structured, with the ability to prioritize development goals effectively.

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Excellent time-management skills and ability to meet deadlines in a fast-paced environment.

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Strong analytical and problem-solving skills, with the ability to work independently.

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Resilient and adaptable in high-pressure or rapidly changing environments.

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Excellent communication skills and ability to collaborate in an interdisciplinary, multicultural team

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